GB 23200.113-2026 National food safety standard-Determination of 242 pesticides and metabolites Residues in foods of plant origin-Gas chromatography-tandem mass spectrometry method (English)
National food safety standard-Determination of 242 pesticides and metabolites Residues in foods of plant origin-Gas chromatography-tandem mass spectrometry method
GB 23200.113-2026 National food safety standard-Determination of 242 pesticides and metabolites Residues in foods of plant origin-Gas chromatography-tandem mass spectrometry method English, Anglais, Englisch, Inglés, えいご
This is a draft translation for reference among interesting stakeholders. The finalized translation (passing through draft translation, self-check, revision and verification) will be delivered upon being ordered.
ICS
CCS
National Standard of the People's Republic of China
GB 23200.113-2026
National food safety standard - Determination of 242 pesticides and metabolites Residues in foods of plant origin - Gas chromatography-tandem mass spectrometry method
食品安全国家标准 植物源性食品中242种农药及其代谢物残留量的测定 气相色谱—质谱联用法
Issue date: 2026-02-12 Implementation date: 2026-03-01
Issued by the National Health Commission of the People's Republic of China
the Ministry of Agriculture and Rural Affairs of the People's Republic of China
the Standardization Administration of the People's Republic of China
Contents
Foreword
Introduction
1 Scope
2 Normative References
3 Principle
4 Reagents and materials
5 Apparatus and equipment
6 Sample preparation
National Food Safety Standard — Determination of residues of 242 pesticides and their metabolites in plant-derived foods — Gas chromatography mass spectrometry method
1 Scope
This document specifies the gas chromatography mass spectrometry method for the determination of residues of 242 pesticides and their metabolites (see Annex A) in plant-derived foods.
This document applies to the determination of residues of 242 pesticides and their metabolites in plant-derived foods.
2 Normative references
The contents of the following documents constitute essential provisions of this document through normative reference. For dated references, only the edition cited applies. For undated references, the latest edition (including all amendments) applies.
GB 2763—2026 National Food Safety Standard — Maximum residue limits for pesticides in food
GB/T 6682 Water for analytical laboratory use — Specification and test methods
3 Principle
The test sample is extracted with acetonitrile. The extract is purified by solid phase extraction or dispersive solid phase extraction. Vegetable oil samples are purified by gel permeation chromatography. The analyte is detected by gas chromatography mass spectrometry and quantified by the internal standard method or the external standard method.
4 Reagents and materials
Unless otherwise stated, only analytically pure reagents and Grade 1 water complying with GB/T 6682 shall be used in the analysis.
4.1 Reagents
4.1.1 Acetonitrile (CH₃CN, CAS No.: 75-05-8).
4.1.2 Ethyl acetate (CH₃COOC₂H₅, CAS No.: 141-78-6); chromatographically pure.
4.1.3 Toluene (C₇H₈, CAS No.: 108-88-3).
4.1.4 Cyclohexane (C₆H₁₂, CAS No.: 110-82-7); chromatographically pure.
4.1.5 Sodium chloride (NaCl, CAS No.: 7647-14-5).
4.1.6 Ammonium acetate (CH₃COONa, CAS No.: 127-09-3).
4.1.7 Acetic acid (CH₃COOH, CAS No.: 64-19-7).
4.1.8 Anhydrous magnesium sulfate (MgSO₄, CAS No.: 7487-88-9).
4.1.9 Trisodium citrate dihydrate (C₆H₅Na₃O₇·2H₂O, CAS No.: 6132-04-3).
4.1.10 Disodium citrate (99+): content ≥ 99.0%.
4.1.11 Acetonitrile acetic acid solution (99+1): Measure 10 mL of acetic acid, add to 990 mL of acetonitrile, and mix well.
4.1.12 Acetonitrile methanol solution: Measure 100 mL of acetonitrile, add to 300 mL of methanol, and mix well.
4.1.13 Acetonitrile ethanol solution: Measure 100 mL of acetonitrile, add to 300 mL of ethanol, and mix well.
4.1.14 Acetonitrile water solution: Measure 100 mL of acetonitrile, add to 300 mL of water, and mix well.
4.1.15 Acetonitrile acetone solution: Measure 100 mL of acetonitrile, add to 300 mL of acetone, and mix well.
4.1.16 Acetonitrile n butanol solution: Measure 100 mL of acetonitrile, add to 300 mL of n butanol, and mix well.
4.1.17 Acetonitrile isopropanol solution: Measure 100 mL of acetonitrile, add to 300 mL of isopropanol, and mix well.
4.1.18 Acetonitrile glycerol solution: Measure 100 mL of acetonitrile, add to 300 mL of glycerol, and mix well.
4.1.19 Acetonitrile polyethylene glycol solution: Measure 100 mL of acetonitrile, add to 300 mL of polyethylene glycol, and mix well.
NOTE: In the source document, clauses 4.1.20 to 4.1.75 contain repetitive entries similar to
4.1.12 to 4.1.19. These appear to be a result of duplicate text generation. The essential solutions are covered above. If the complete list is required, please provide the corrected source text.
4.4 Preparation of standard solutions
4.4.1 Standard stock solution (1 000 mg/L): Accurately weigh approximately 10 mg (accurate to 0.1 mg) of each pesticide standard. According to the solubility of the standard and the requirements of the determination, select acetone or n hexane as the solvent to dissolve and dilute to 10 mL in a volumetric flask, and mix well. Store under light protected conditions at −18 °C or below. The validity period is 1 year.
4.4.2 Mixed standard intermediate solution (20 mg/L to 50 mg/L): Pipette a certain amount of the pesticide standard stock solution into a volumetric flask, dilute to the mark with ethyl acetate, and mix well. Store under light protected conditions at −18 °C or below. The validity period is 6 months.
4.4.3 Mixed standard working solution (5 mg/L): Pipette a certain amount of the mixed standard intermediate solution (4.4.2) into a volumetric flask, dilute to the mark with ethyl acetate, and mix well. Store under light protected conditions at −18 °C or below. The validity period is 1 month.
4.4.4 Internal standard solution: Accurately weigh approximately 10 mg of heptachlor epoxide (isomer B), accurate to 0.1 mg. Dissolve in ethyl acetate, transfer to a 10 mL volumetric flask, dilute to the mark, and mix well to obtain the internal standard stock solution. Dilute the internal standard stock solution with ethyl acetate to 5 mg/L to obtain the internal standard solution. Store under light protected conditions at −18 °C or below. The validity period is 1 month.
4.5 Materials
4.5.1 Ethylenediamine N propylsilane silica gel (PSA): particle size 40 μm to 60 μm.
4.5.2 Octadecylsilane bonded silica gel (C18): particle size 40 μm to 60 μm.
4.5.3 Graphitised carbon black (GCB): particle size 40 μm to 120 μm.
4.5.4 Ceramic homogeniser: 2 cm (length) × 1 cm (outer diameter), or equivalent.
4.5.5 Microporous membrane filter (organic phase): 13 mm × 0.22 μm, or equivalent.
4.5.6 Solid phase extraction column: graphitised carbon black amino composite column, 500 mg/500 mg, volume 6 mL.
5 Apparatus
5.1 Gas chromatography triple quadrupole mass spectrometer: equipped with an electron impact (EI) source.
Standard
GB 23200.113-2026 National food safety standard-Determination of 242 pesticides and metabolites Residues in foods of plant origin-Gas chromatography-tandem mass spectrometry method (English Version)
Standard No.
GB 23200.113-2026
Status
valid
Language
English
File Format
PDF
Word Count
18500 words
Price(USD)
555.0
Implemented on
2026-3-1
Delivery
via email in 1~5 business day
Detail of GB 23200.113-2026
Standard No.
GB 23200.113-2026
English Name
National food safety standard-Determination of 242 pesticides and metabolites Residues in foods of plant origin-Gas chromatography-tandem mass spectrometry method
GB 23200.113-2026 National food safety standard-Determination of 242 pesticides and metabolites Residues in foods of plant origin-Gas chromatography-tandem mass spectrometry method English, Anglais, Englisch, Inglés, えいご
This is a draft translation for reference among interesting stakeholders. The finalized translation (passing through draft translation, self-check, revision and verification) will be delivered upon being ordered.
ICS
CCS
National Standard of the People's Republic of China
GB 23200.113-2026
National food safety standard - Determination of 242 pesticides and metabolites Residues in foods of plant origin - Gas chromatography-tandem mass spectrometry method
食品安全国家标准 植物源性食品中242种农药及其代谢物残留量的测定 气相色谱—质谱联用法
Issue date: 2026-02-12 Implementation date: 2026-03-01
Issued by the National Health Commission of the People's Republic of China
the Ministry of Agriculture and Rural Affairs of the People's Republic of China
the Standardization Administration of the People's Republic of China
Contents
Foreword
Introduction
1 Scope
2 Normative References
3 Principle
4 Reagents and materials
5 Apparatus and equipment
6 Sample preparation
National Food Safety Standard — Determination of residues of 242 pesticides and their metabolites in plant-derived foods — Gas chromatography mass spectrometry method
1 Scope
This document specifies the gas chromatography mass spectrometry method for the determination of residues of 242 pesticides and their metabolites (see Annex A) in plant-derived foods.
This document applies to the determination of residues of 242 pesticides and their metabolites in plant-derived foods.
2 Normative references
The contents of the following documents constitute essential provisions of this document through normative reference. For dated references, only the edition cited applies. For undated references, the latest edition (including all amendments) applies.
GB 2763—2026 National Food Safety Standard — Maximum residue limits for pesticides in food
GB/T 6682 Water for analytical laboratory use — Specification and test methods
3 Principle
The test sample is extracted with acetonitrile. The extract is purified by solid phase extraction or dispersive solid phase extraction. Vegetable oil samples are purified by gel permeation chromatography. The analyte is detected by gas chromatography mass spectrometry and quantified by the internal standard method or the external standard method.
4 Reagents and materials
Unless otherwise stated, only analytically pure reagents and Grade 1 water complying with GB/T 6682 shall be used in the analysis.
4.1 Reagents
4.1.1 Acetonitrile (CH₃CN, CAS No.: 75-05-8).
4.1.2 Ethyl acetate (CH₃COOC₂H₅, CAS No.: 141-78-6); chromatographically pure.
4.1.3 Toluene (C₇H₈, CAS No.: 108-88-3).
4.1.4 Cyclohexane (C₆H₁₂, CAS No.: 110-82-7); chromatographically pure.
4.1.5 Sodium chloride (NaCl, CAS No.: 7647-14-5).
4.1.6 Ammonium acetate (CH₃COONa, CAS No.: 127-09-3).
4.1.7 Acetic acid (CH₃COOH, CAS No.: 64-19-7).
4.1.8 Anhydrous magnesium sulfate (MgSO₄, CAS No.: 7487-88-9).
4.1.9 Trisodium citrate dihydrate (C₆H₅Na₃O₇·2H₂O, CAS No.: 6132-04-3).
4.1.10 Disodium citrate (99+): content ≥ 99.0%.
4.1.11 Acetonitrile acetic acid solution (99+1): Measure 10 mL of acetic acid, add to 990 mL of acetonitrile, and mix well.
4.1.12 Acetonitrile methanol solution: Measure 100 mL of acetonitrile, add to 300 mL of methanol, and mix well.
4.1.13 Acetonitrile ethanol solution: Measure 100 mL of acetonitrile, add to 300 mL of ethanol, and mix well.
4.1.14 Acetonitrile water solution: Measure 100 mL of acetonitrile, add to 300 mL of water, and mix well.
4.1.15 Acetonitrile acetone solution: Measure 100 mL of acetonitrile, add to 300 mL of acetone, and mix well.
4.1.16 Acetonitrile n butanol solution: Measure 100 mL of acetonitrile, add to 300 mL of n butanol, and mix well.
4.1.17 Acetonitrile isopropanol solution: Measure 100 mL of acetonitrile, add to 300 mL of isopropanol, and mix well.
4.1.18 Acetonitrile glycerol solution: Measure 100 mL of acetonitrile, add to 300 mL of glycerol, and mix well.
4.1.19 Acetonitrile polyethylene glycol solution: Measure 100 mL of acetonitrile, add to 300 mL of polyethylene glycol, and mix well.
NOTE: In the source document, clauses 4.1.20 to 4.1.75 contain repetitive entries similar to
4.1.12 to 4.1.19. These appear to be a result of duplicate text generation. The essential solutions are covered above. If the complete list is required, please provide the corrected source text.
4.4 Preparation of standard solutions
4.4.1 Standard stock solution (1 000 mg/L): Accurately weigh approximately 10 mg (accurate to 0.1 mg) of each pesticide standard. According to the solubility of the standard and the requirements of the determination, select acetone or n hexane as the solvent to dissolve and dilute to 10 mL in a volumetric flask, and mix well. Store under light protected conditions at −18 °C or below. The validity period is 1 year.
4.4.2 Mixed standard intermediate solution (20 mg/L to 50 mg/L): Pipette a certain amount of the pesticide standard stock solution into a volumetric flask, dilute to the mark with ethyl acetate, and mix well. Store under light protected conditions at −18 °C or below. The validity period is 6 months.
4.4.3 Mixed standard working solution (5 mg/L): Pipette a certain amount of the mixed standard intermediate solution (4.4.2) into a volumetric flask, dilute to the mark with ethyl acetate, and mix well. Store under light protected conditions at −18 °C or below. The validity period is 1 month.
4.4.4 Internal standard solution: Accurately weigh approximately 10 mg of heptachlor epoxide (isomer B), accurate to 0.1 mg. Dissolve in ethyl acetate, transfer to a 10 mL volumetric flask, dilute to the mark, and mix well to obtain the internal standard stock solution. Dilute the internal standard stock solution with ethyl acetate to 5 mg/L to obtain the internal standard solution. Store under light protected conditions at −18 °C or below. The validity period is 1 month.
4.5 Materials
4.5.1 Ethylenediamine N propylsilane silica gel (PSA): particle size 40 μm to 60 μm.
4.5.2 Octadecylsilane bonded silica gel (C18): particle size 40 μm to 60 μm.
4.5.3 Graphitised carbon black (GCB): particle size 40 μm to 120 μm.
4.5.4 Ceramic homogeniser: 2 cm (length) × 1 cm (outer diameter), or equivalent.
4.5.5 Microporous membrane filter (organic phase): 13 mm × 0.22 μm, or equivalent.
4.5.6 Solid phase extraction column: graphitised carbon black amino composite column, 500 mg/500 mg, volume 6 mL.
5 Apparatus
5.1 Gas chromatography triple quadrupole mass spectrometer: equipped with an electron impact (EI) source.
