This standard specifies liquid chromatography tandem mass spectrometry of nonylphenol in cosmetics.
This standard applies to the determination of nonylphenol in such cosmetics as cream, loose powder, waters and lipstick.
For the purpose of this standard, the detection limit and quantitation limit of nonylphenol are 0.1 mg/kg and 0.2 mg/kg respectively.
2 Normative References
The following documents are indispensable for application of this standard. Any dated reference, only dated edition applies. For the undated reference, the latest edition (including any amendments) applies.
GB/T 6682 Water for Analytical Laboratory Use - Specification and Test Methods
3 Principle
Extract nonylphenol in cosmetics with methyl alcohol - methylene chloride mixed solution, purify the extracting solution by centrifugation and solid-phase extraction column, determine by liquid chromatography tandem mass spectrometry and quantify by internal standard method.
4 Reagents and Materials
Foreword i Introduction ii 1 Scope 2 Normative References 3 Principle 4 Reagents and Materials 5 Apparatus 6 Determination Procedure 7 Result Calculation 8 Detection Limit and Quantitation Limit 9 Recovery Rate and Precision 10 Permissible Deviation Annex A (Informative) Structural Formula of Nonylphenol Standard Annex B (Informative) Selected Iron Mass Chromatogram of Nonylphenol Standard and Internal Standard Substance
Standard
GB/T 29675-2013 Determination of nonylphenol in cosmetics—Liquid chromatography tandem mass spectrometry (English Version)
Standard No.
GB/T 29675-2013
Status
valid
Language
English
File Format
PDF
Word Count
6000 words
Price(USD)
180.0
Implemented on
2014-2-15
Delivery
via email in 1~3 business day
Detail of GB/T 29675-2013
Standard No.
GB/T 29675-2013
English Name
Determination of nonylphenol in cosmetics—Liquid chromatography tandem mass spectrometry
1 Scope
This standard specifies liquid chromatography tandem mass spectrometry of nonylphenol in cosmetics.
This standard applies to the determination of nonylphenol in such cosmetics as cream, loose powder, waters and lipstick.
For the purpose of this standard, the detection limit and quantitation limit of nonylphenol are 0.1 mg/kg and 0.2 mg/kg respectively.
2 Normative References
The following documents are indispensable for application of this standard. Any dated reference, only dated edition applies. For the undated reference, the latest edition (including any amendments) applies.
GB/T 6682 Water for Analytical Laboratory Use - Specification and Test Methods
3 Principle
Extract nonylphenol in cosmetics with methyl alcohol - methylene chloride mixed solution, purify the extracting solution by centrifugation and solid-phase extraction column, determine by liquid chromatography tandem mass spectrometry and quantify by internal standard method.
4 Reagents and Materials
Contents of GB/T 29675-2013
Foreword i
Introduction ii
1 Scope
2 Normative References
3 Principle
4 Reagents and Materials
5 Apparatus
6 Determination Procedure
7 Result Calculation
8 Detection Limit and Quantitation Limit
9 Recovery Rate and Precision
10 Permissible Deviation
Annex A (Informative) Structural Formula of Nonylphenol Standard
Annex B (Informative) Selected Iron Mass Chromatogram of Nonylphenol Standard and Internal Standard Substance
